Gene: BRAF ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs113488022
rs113488022
BRAF
T 0.790 CausalMutation CLINVAR Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. 19001320

2008
dbSNP: rs113488022
rs113488022
BRAF
T 0.790 CausalMutation CLINVAR Vemurafenib synergizes with nutlin-3 to deplete survivin and suppresses melanoma viability and tumor growth. 23812671

2013
dbSNP: rs113488022
rs113488022
BRAF
T 0.790 CausalMutation CLINVAR Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. 22281684

2012
dbSNP: rs121913338
rs121913338
BRAF
C 0.700 CausalMutation CLINVAR The road to resistance: EGFR mutation and cetuximab. 22310681

2012
dbSNP: rs121913351
rs121913351
BRAF
A 0.700 CausalMutation CLINVAR The road to resistance: EGFR mutation and cetuximab. 22310681

2012
dbSNP: rs121913355
rs121913355
BRAF
A 0.700 CausalMutation CLINVAR The road to resistance: EGFR mutation and cetuximab. 22310681

2012
dbSNP: rs121913355
rs121913355
BRAF
G 0.700 CausalMutation CLINVAR The road to resistance: EGFR mutation and cetuximab. 22310681

2012
dbSNP: rs121913355
rs121913355
BRAF
T 0.700 CausalMutation CLINVAR The road to resistance: EGFR mutation and cetuximab. 22310681

2012
dbSNP: rs121913361
rs121913361
BRAF
G 0.700 CausalMutation CLINVAR The road to resistance: EGFR mutation and cetuximab. 22310681

2012
dbSNP: rs113488022
rs113488022
BRAF
T 0.790 CausalMutation CLINVAR Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents. 23251002

2013
dbSNP: rs121913351
rs121913351
BRAF
A 0.700 CausalMutation CLINVAR Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). 18186519

2008
dbSNP: rs121913355
rs121913355
BRAF
G 0.700 CausalMutation CLINVAR Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). 18186519

2008
dbSNP: rs121913355
rs121913355
BRAF
A 0.700 CausalMutation CLINVAR Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). 18186519

2008
dbSNP: rs121913355
rs121913355
BRAF
T 0.700 CausalMutation CLINVAR Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). 18186519

2008
dbSNP: rs121913338
rs121913338
BRAF
C 0.700 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913361
rs121913361
BRAF
G 0.700 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs113488022
rs113488022
BRAF
T 0.790 CausalMutation CLINVAR Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? 21129611

2010
dbSNP: rs121913338
rs121913338
BRAF
C 0.700 CausalMutation CLINVAR Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? 21129611

2010
dbSNP: rs121913351
rs121913351
BRAF
A 0.700 CausalMutation CLINVAR Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? 21129611

2010
dbSNP: rs121913355
rs121913355
BRAF
G 0.700 CausalMutation CLINVAR Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? 21129611

2010
dbSNP: rs121913355
rs121913355
BRAF
A 0.700 CausalMutation CLINVAR Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? 21129611

2010
dbSNP: rs121913355
rs121913355
BRAF
T 0.700 CausalMutation CLINVAR Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? 21129611

2010
dbSNP: rs121913361
rs121913361
BRAF
G 0.700 CausalMutation CLINVAR Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? 21129611

2010
dbSNP: rs113488022
rs113488022
BRAF
T 0.790 CausalMutation CLINVAR Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery. 20350999

2010
dbSNP: rs121913338
rs121913338
BRAF
C 0.700 CausalMutation CLINVAR Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery. 20350999

2010